Rag2-Il2rg double knockout mice (R2G2®)

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  • Coat white-bellied, light chinchilla (light tan)
  • Common gamma chain gene (II2rg) interrupted
  • Decreased dendritic cells
  • Decreased macrophage cells
  • Decreased neutrophils
  • Deficient in T and B cells
  • Lacks functional receptors for IL-2, IL-4, IL-7, IL-9 and IL-15
  • Lacks NK cells
  • Recombination activating gene 2 (Rag2) interrupted
  • Severe lymphocyte development impairment
Product Code:
Brand: Envigo

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